Carbon dioxide therapy (CDT), or carboxytherapy, is not a new technique within medical practice. Developed in France during the 1930s, it was found that bathing in pools of carbon dioxide-rich water helped to speed up wound healing. By the 1950s, the technique was used by cardiologists to treat patients with peripheral arterial occlusive disease, as well as other conditions caused by poor blood circulation and fat accumulation in the arteries. Since 1995, when the term ‘carboxytherapy’ was coined, it has increased in popularity in the field of aesthetics, and particularly for lipolysis1, 2 and dermal rejuvenation treatments. . Indeed, studies have demonstrated that CDT improves skin elasticity, circulation and the appearance of fine lines and wrinkles, aids collagen repair, and destroys localised fatty deposits